Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 12/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963055 | 0.82 | BLM (0.50) | PPARAPPARGPPARDADORA3ALDH1A1 | |
| SCHEMBL5197222 | 0.82 | BLM (0.50) | PPARAPPARGPPARDADORA3ALDH1A1 | |
| SCHEMBL5365631 | 0.81 | PPARA (0.49) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL6396442 | 0.81 | PPARA (0.48) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL5365344 | 0.80 | CXCR2 (0.40) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL6387462 | 0.80 | LMNA (0.47) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL7777170 | 0.80 | LMNA (0.47) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL5367481 | 0.77 | PPARA (0.41) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL4459836 | 0.75 | PPARG (0.51) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL4459833 | 0.75 | PPARG (0.51) | PPARAPPARGPPARDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |