Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417591 | 0.90 | TSHR (0.51) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL8860983 | 0.78 | CYP19A1 (0.75) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL27053588 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL11046243 | 0.76 | TSHR (0.49) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5049441 | 0.76 | CYP19A1 (0.71) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL6761969 | 0.76 | CYP19A1 (0.66) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL28258808 | 0.75 | ALDH1A1 (0.49) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL27820726 | 0.75 | CYP19A1 (0.71) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL1301606 | 0.75 | CYP19A1 (0.71) | TSHRALDH1A1MAPK1L3MBTL1CYP19A1 | |
| SCHEMBL5120138 | 0.74 | CYP19A1 (0.52) | ALDH1A1MAPK1L3MBTL1CYP19A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476011-B1 | Construction and use of catalogued nucleic acid libraries that contain advantageously adjusted representations of defined components | BP CORPORATION NORTH AMERICA INC. (US) | 2013-07-02 | — | — | US | disclosed |