Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284003 | 1.00 | HTT (0.53) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL10902321 | 0.94 | POLB (0.49) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL10737844 | 0.94 | POLB (0.49) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL10737849 | 0.94 | POLB (0.49) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL3319559 | 0.94 | PKM (0.54) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL2576204 | 0.94 | PKM (0.54) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL10450410 | 0.92 | HTT (0.55) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL5478099 | 0.92 | HTT (0.55) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL10393841 | 0.92 | HTT (0.55) | HTTLMNAMAPK1POLBHPGD | |
| SCHEMBL9406241 | 0.92 | HTT (0.55) | HTTLMNAMAPK1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351587-B2 | Method of making and using 7α, 11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-07-16 | — | — | US | disclosed |
| US-20110195942-A1 | METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN | 2011-08-11 | — | — | US | disclosed |
| EP-1873228-B1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL, OPTICAL ELEMENT, AND OPTICAL HEAD DEVICE | ASAHI GLASS CO LTD (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-7534370-B2 | Polymerizable liquid crystal composition, optical anisotropic material, optical element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20090023695-A1 | METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2009-01-22 | — | — | US | disclosed |
| US-20080048149-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1873228-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL, OPTICAL ELEMENT, AND OPTICAL HEAD DEVICE | Asahi Glass Company, Limited (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-7196074-B2 | Methods of making, using and pharmaceutical formulations comprising 7α, 11β-dimethyl-17β-hydroxyestra-4, 14-dien-3-one and 17 esters thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1272196-B1 | METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA,11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE | US GOV HEALTH & HUMAN SERV (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1379253-B1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA,11BETA-DIMETHYL-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | US GOV HEALTH & HUMAN SERV (US) | 2006-03-29 | — | — | EP | disclosed |
| US-5348677-A | Electro-optical liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-20 | — | — | US | disclosed |
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| US-5196140-A | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0315958-B1 | OPTICALLY ACTIVE MESOMORPHIC COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | CANON KABUSHIKI KAISHA (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0400861-A1 | 1,3-dioxane derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORPORATION (JP) | 1990-12-05 | — | — | EP | disclosed |
| US-4948790-A | Long-acting androgenic compounds and pharmaceutical compositions thereof | ARCHER SYDNEY (US) | 1990-08-14 | — | — | US | disclosed |
| US-4917821-A | Optically active mesomorphic compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0315958-A2 | Optically active mesomorphic compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |
| US-4490278-A | Liquid crystal substituted trans-4-n-alkylcyclohexanes and subst.-3-subst.-benzoyloxy-[trans-4-n-alkylcyclohexane]s | VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DE) | 1984-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023695-A1 | METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | HSD17B11, HSD17B13, HSD3B1 | HTT 574/4885LMNA 1122/4885MAPK1 3161/4885 |
| US-20110195942-A1 | METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | HSD17B11, HSD17B13, HSD3B1 | HTT 574/4885LMNA 1122/4885MAPK1 3161/4885 |
| US-10351587-B2 | Method of making and using 7α, 11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate | HSD17B11, HSD17B13, CYP19A1 | HTT 367/4885LMNA 933/4885MAPK1 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.