Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL31286303 | 0.92 | PSIP1 (0.41) | PSIP1CHRM4CHRM1CHRM3CES2 | |
| SCHEMBL29049262 | 0.90 | PSIP1 (0.40) | PSIP1TSHRSMN1; SMN2CHRM4CHRM1 | |
| SCHEMBL21957777 | 0.90 | PSIP1 (0.40) | PSIP1CA12CA2CA9PTGS2 | |
| Sulfuric Acid SCHEMBL1534138 | 0.85 | DNM1 (0.41) | SMN1; SMN2CHRM1CHRM3CES2CES1 | |
| SCHEMBL21957767 | 0.85 | BCHE (0.41) | PSIP1CHRM4CHRM1CHRM3CA12 | |
| Sulfuric Acid SCHEMBL10802033 | 0.84 | PSIP1 (0.39) | PSIP1TSHRSMN1; SMN2CES2CES1 | |
| Bicarbonate SCHEMBL21957729 | 0.83 | CES2 (0.43) | TSHRCHRM4CHRM1CHRM3CES2 | |
| Trifluoromethanesulfonic Acid SCHEMBL21957811 | 0.83 | KCNH2 (0.44) | PSIP1 | |
| Bicarbonate SCHEMBL21957730 | 0.83 | CHRM1 (0.43) | TSHRSMN1; SMN2CHRM4CHRM1CHRM3 | |
| SCHEMBL11417691 | 0.83 | APOBEC3A (0.42) | TSHRSMN1; SMN2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206673-B2 | Method of preparing boron-nitrogen compounds | WILDCAT DISCOVERY TECHNOLOGIES (US) | 2012-06-26 | — | — | US | disclosed |
| US-20110064640-A1 | METHOD OF PREPARING BORON-NITROGEN COMPOUNDS | WILDCAT DISCOVERY TECHNOLOGIES (US) | 2011-03-17 | — | — | US | disclosed |
| US-4144265-A | CHLOROMETHYLATION, CYANATION OF TRIFLUOROMETHYL BENZENE | THE DOW CHEMICAL COMPANY (US) | 1979-03-13 | — | — | US | disclosed |
| US-4141916-A | 3,4,5-Trichloro-N,N-Di(loweralkyl)-2-((chloromethyl)thio)benzenesulfonamides | THE DOW CHEMICAL COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4094873-A | Process for preparing phosphorothioates and phenylphosphonothioates | THE DOW CHEMICAL COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4092312-A | CATALYST SYSTEM OF A QUATERNARY AMMONIUM SALT AND 1,4-DIAZABICYCLO(2.2.2)OCTANE | THE DOW CHEMICAL COMPANY (US) | 1978-05-30 | — | — | US | disclosed |
| US-4061682-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | THE DOW CHEMICAL COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4028439-A | QUATERNARY AMMONIUM SALT AND IMIDAZOLE CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4016225-A | WITH QUATERNARY AMMONIUM SALT AND 1,4-DIAZABICYCLO(2.2.2)OCTANE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4014891-A | FROM AN ALKALI METAL ARYL MERCAPTIDE AND BROMOCHLOROMETHANE IN A QUATERNARY AMMONIUM SALT | THE DOW CHEMICAL COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-4001293-A | Process for production of γ-halonitriles | THE DOW CHEMICAL COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3974199-A | Process for production of cyclopropylcyanide | THE DOW CHEMICAL COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
| US-3972887-A | QUATERNARY AMMONIUM SALT CATALYST | THE DOW CHEMICAL COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3969360-A | Catalyzed alkylation of halopyridinates | THE DOW CHEMICAL COMPANY (US) | 1976-07-13 | — | — | US | disclosed |