Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3325673 | 0.85 | TRPV1 (0.46) | TRPV1P2RX7HTR2AHTR2CHTR2B | |
| SCHEMBL3325669 | 0.85 | TRPV1 (0.46) | TRPV1P2RX7HTR2AHTR2CHTR2B | |
| SCHEMBL15160099 | 0.79 | KDM4E (0.36) | TRPV1P2RX7HTR2AHTR2CHTR2B | |
| SCHEMBL1154206 | 0.79 | POLL (0.45) | ACHEBCHE | |
| SCHEMBL15158685 | 0.77 | ACHE (0.36) | TRPV1P2RX7HTR2AHTR2CHTR2B | |
| SCHEMBL3322936 | 0.76 | TRPM8 (0.39) | TRPV1HTR2AHTR2CHTR2BTRPM8 | |
| SCHEMBL3322941 | 0.76 | TRPM8 (0.39) | TRPV1HTR2AHTR2CHTR2BTRPM8 | |
| SCHEMBL1508231 | 0.76 | FFAR1 (0.41) | TRPV1P2RX7HTR2CHTR2B | |
| SCHEMBL1508366 | 0.76 | FFAR1 (0.41) | TRPV1P2RX7HTR2CHTR2B | |
| SCHEMBL3322927 | 0.74 | TRPM8 (0.38) | TRPV1P2RX7HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-B1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-8222281-B2 | Carboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | AKR1C3, SLC5A1, GPR119 | TRPV1 1400/4885P2RX7 3619/4885HTR2A 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.