Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MDH2 | P40926 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508157 | 0.87 | CYP2D6 (0.50) | CYP2D6MAOBMRGPRX4MAOAPTPN1 | |
| SCHEMBL31395253 | 0.87 | CYP2D6 (0.53) | CYP2D6MAOBMRGPRX4MAOAPTPN1 | |
| SCHEMBL13221277 | 0.87 | PDGFRA (0.50) | CYP2D6MAOBMRGPRX4MAOAPTPN1 | |
| SCHEMBL11118881 | 0.85 | MRGPRX4 (0.59) | CYP2D6MAOBMRGPRX4MAOAPTPN1 | |
| SCHEMBL14102978 | 0.85 | NPC1 (0.61) | MAOBFFAR1MEN1KMT2A | |
| SCHEMBL366446 | 0.85 | ALDH1A1 (0.55) | CYP2D6MAOBMRGPRX4MAOAPTPN1 | |
| SCHEMBL190184 | 0.83 | HPGD (0.58) | MAOBMRGPRX4MAOAS1PR1S1PR5 | |
| SCHEMBL31395176 | 0.83 | MAOB (0.46) | CYP2D6MAOBMRGPRX4MAOAPTPN1 | |
| SCHEMBL3038004 | 0.81 | RAB9A (0.63) | MAOBMAOAPTPN1FFAR1PLAT | |
| SCHEMBL9128904 | 0.81 | RAB9A (0.55) | MAOBMRGPRX4MAOAPTPN1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222281-B2 | Carboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | AKR1C3, SLC5A1, GPR119 | CYP2D6 358/4885MAOB 904/4885MRGPRX4 1075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.