SCHEMBL1508330

SCHEMBL1508330

CCO[C@@H](CC(=O)OC)c1ccc(O[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.42
PPARG P37231 1/20 0.41
PREP P48147 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1508290 0.90 FFAR1 (0.45) FFAR1PPARG
SCHEMBL10317583 0.87 FFAR1 (0.55) FFAR1PPARG
SCHEMBL15687667 0.82 DRD2 (0.41) FFAR1PREP
SCHEMBL1508406 0.82 PREP (0.42) PREP
SCHEMBL7455145 0.81 PREP (0.41) PREP
SCHEMBL7237737 0.81 PREP (0.41) PREP
SCHEMBL1508431 0.77 FFAR1 (0.46) FFAR1PPARG
SCHEMBL17493569 0.77 FFAR1 (0.39) FFAR1PREP
SCHEMBL17493578 0.77 FFAR1 (0.39) FFAR1PREP
SCHEMBL14762467 0.76 PREP (0.39) FFAR1PPARGPREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110053974-A1 CARBOXYLIC ACID COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-03-03 US disclosed
EP-2289868-A1 CARBOXYLIC ACID COMPOUND Daiichi Sankyo Company, Limited (JP) 2011-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053974-A1 CARBOXYLIC ACID COMPOUND AKR1C3, SLC5A1, GPR119 FFAR1 219/4885PPARG 200/4885PREP 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.