Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 0.37 |
| ▸ | CD63 | P08962 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16844846 | 0.92 | TLR9 (0.36) | PTK2 | |
| SCHEMBL15086236 | 0.86 | TLR9 (0.38) | — | |
| SCHEMBL15086251 | 0.84 | TLR9 (0.38) | SYK | |
| SCHEMBL15086479 | 0.84 | ADRB1 (0.38) | PIM1PIM3PIM2 | |
| SCHEMBL15086290 | 0.82 | ADRA2A (0.33) | — | |
| SCHEMBL15086244 | 0.82 | SUV39H2 (0.38) | — | |
| SCHEMBL15086313 | 0.82 | GHSR (0.33) | — | |
| SCHEMBL15086238 | 0.82 | FLT3 (0.33) | SYK | |
| SCHEMBL15086361 | 0.81 | SUV39H2 (0.38) | PIM1PIM3PIM2 | |
| SCHEMBL15086497 | 0.81 | PIM1 (0.38) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013101974-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |