SCHEMBL15086604

SCHEMBL15086604

Cc1ccc(C=O)c(O)c1COC=O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.38
TYR P14679 2/20 0.38
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
TLR2 O60603 1/20 0.38
TLR1 Q15399 1/20 0.38
TLR6 Q9Y2C9 1/20 0.38
SRC P12931 2/20 0.33
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
IGF1R P08069 1/20 0.33
AXL P30530 1/20 0.33
PTK2 Q05397 1/20 0.33
AURKB Q96GD4 1/20 0.33
ALK Q9UM73 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19124361 0.81 ERN1 (0.39) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL15086598 0.79 ERN1 (0.41) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL13321963 0.78 KDM4E (0.40) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL19123886 0.76 ERN1 (0.38) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL2088680 0.72 SLC22A12 (0.38) TRIM24TRIM33SRCALDH1A1TSHR
SCHEMBL28639767 0.72 ALOX5 (0.41) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL29933713 0.72 ALOX5 (0.41) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL452160 0.72 ERN1 (0.48) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL3065272 0.70 ERN1 (0.46) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL4580995 0.69 ERN1 (0.45) ERN1TYRTRIM24TRIM33TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9046764-B2 Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
US-20130171569-A1 RESIST UNDERLAYER FILM COMPOSITION, METHOD FOR PRODUCING POLYMER FOR RESIST UNDERLAYER FILM, AND PATTERNING PROCESS USING THE RESIST UNDERLAYER FILM COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-07-04 US disclosed