Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 4/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19124361 | 0.86 | ERN1 (0.39) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL3957273 | 0.82 | SRD5A1 (0.45) | KDM4EGAAERN1ALDH1A1SRD5A1 | |
| SCHEMBL8316943 | 0.81 | GABRA1 (0.39) | KDM4EGAAGLAALDH1A1SRD5A1 | |
| SCHEMBL15086598 | 0.80 | ERN1 (0.41) | KDM4EERN1TLR2TLR1TLR6 | |
| SCHEMBL22297592 | 0.79 | ERN1 (0.38) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL3333141 | 0.79 | ERN1 (0.50) | KDM4EERN1TLR2TLR1TLR6 | |
| SCHEMBL1053052 | 0.78 | XDH (0.42) | KDM4EGAAGLAALDH1A1SRD5A1 | |
| SCHEMBL15086604 | 0.78 | ERN1 (0.38) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL19123886 | 0.77 | ERN1 (0.38) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL29829217 | 0.77 | GABRA1 (0.48) | KDM4EGAAGLAALDH1A1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144729-A1 | COUMARIN DERIVATIVES | NOVARTIS AG (CH) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144729-A1 | COUMARIN DERIVATIVES | F3, CYP3A7, CYP3A4 | KDM4E 2754/4885GAA 2463/4885GLA 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.