Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639767 | 1.00 | ALOX5 (0.41) | ALOX5PTGS1PTGS2ERN1LPL | |
| SCHEMBL29933734 | 0.79 | ALOX5 (0.41) | ALOX5PTGS1PTGS2ERN1LPL | |
| SCHEMBL28653235 | 0.79 | ALOX5 (0.41) | ALOX5PTGS1PTGS2ERN1LPL | |
| SCHEMBL28644753 | 0.78 | CA1 (0.38) | PTGS2ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29933807 | 0.78 | CA1 (0.38) | PTGS2ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL15086598 | 0.78 | ERN1 (0.41) | ERN1ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL19124361 | 0.76 | ERN1 (0.39) | ERN1ALDH1A1TLR2TLR1TLR6 | |
| SCHEMBL19123886 | 0.75 | ERN1 (0.38) | ERN1ALDH1A1TLR2TLR1TLR6 | |
| SCHEMBL13321963 | 0.73 | KDM4E (0.40) | ERN1ALDH1A1KDM4EGAATLR2 | |
| SCHEMBL15086604 | 0.72 | ERN1 (0.38) | ERN1ALDH1A1TLR2TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461659-B | C-spirocyclic prostaglandin analogue intermediate and preparation method thereof | 上海应用技术大学 | 2022-11-11 | — | — | CN | claimed |
| CN-113461659-B | C-spirocyclic prostaglandin analogue intermediate and preparation method thereof | 上海应用技术大学 | 2022-11-11 | — | — | CN | disclosed |