Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KYNU | Q16719 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508888 | 1.00 | CTSS (0.56) | CTSSCTSLCTSBMAPTL3MBTL1 | |
| SCHEMBL7943021 | 0.91 | CTSS (0.57) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL31173340 | 0.86 | CTSS (0.54) | CTSSCTSLCTSBMAPTCTSK | |
| SCHEMBL27648023 | 0.83 | CTSK (0.56) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL27965014 | 0.83 | CTSS (0.62) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL1840160 | 0.83 | CTSS (0.62) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL17106926 | 0.82 | CYP3A4 (0.56) | CTSSCTSLCTSBMAPTL3MBTL1 | |
| SCHEMBL16464284 | 0.82 | CYP3A4 (0.56) | CTSSCTSLCTSBMAPTL3MBTL1 | |
| SCHEMBL5412160 | 0.81 | MAPT (0.61) | CTSSCTSLCTSBMAPTL3MBTL1 | |
| SCHEMBL939737 | 0.81 | MAPT (0.61) | CTSSCTSLCTSBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |