Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.62 |
| ▸ | CTSL | P07711 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 5/20 | 0.62 |
| ▸ | CTSK | P43235 | 6/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840160 | 1.00 | CTSS (0.62) | CTSSCTSLCTSBCTSKTRPM8 | |
| SCHEMBL27965067 | 0.92 | CTSS (0.63) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL1855255 | 0.92 | CTSS (0.63) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL1837328 | 0.85 | CTSS (0.62) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL1841120 | 0.84 | CTSL (0.61) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL1508888 | 0.83 | CTSS (0.56) | CTSSCTSLCTSBCTSKTRPM8 | |
| SCHEMBL1508675 | 0.83 | CTSS (0.56) | CTSSCTSLCTSBCTSKTRPM8 | |
| SCHEMBL1839814 | 0.83 | CTSS (0.47) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL28812052 | 0.83 | CTSS (0.47) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL1838673 | 0.81 | CTSS (0.48) | CTSSCTSLCTSBCTSKCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370773-B | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD | 2014-04-09 | — | — | CN | disclosed |