SCHEMBL15087398

SCHEMBL15087398

CNC(=O)O[C@@H](C)[C@@H](OC)c1c(Cl)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 3/20 0.35
ACHE P22303 2/20 0.35
POLB P06746 1/20 0.35
NLRP3 Q96P20 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 1/20 0.33
BCHE P06276 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15080128 0.84 CYP2C9 (0.39) HPGDALOX15ALDH1A1ACHEPOLB
SCHEMBL15080014 0.84 CYP2C9 (0.39) HPGDALOX15ALDH1A1ACHEPOLB
SCHEMBL23347721 0.84 CYP2C9 (0.39) HPGDALOX15ALDH1A1ACHEPOLB
SCHEMBL15078562 0.82 CXCL8 (0.35) HPGDALOX15KMT2AMEN1TDP1
SCHEMBL15089442 0.82 HPGD (0.37) HPGDALOX15KMT2AMEN1TDP1
SCHEMBL15078553 0.82 CXCL8 (0.35) HPGDALOX15KMT2AMEN1TDP1
SCHEMBL16064827 0.82 ALDH1A1 (0.40) HPGDALOX15KMT2AMEN1TDP1
SCHEMBL15078514 0.82 CXCL8 (0.35) HPGDALOX15KMT2AMEN1TDP1
SCHEMBL15089434 0.77 ALDH1A1 (0.38) KMT2AMEN1ALDH1A1NLRP3SMN1; SMN2
SCHEMBL20604268 0.73 APLNR (0.31) ACHECYP3A4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed