Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 2/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 4/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088377 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL15800089 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL972213 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL12921440 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL12208780 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL12921348 | 0.91 | — | — | |
| SCHEMBL12948470 | 0.91 | — | — | |
| SCHEMBL12921347 | 0.91 | — | — | |
| SCHEMBL12210438 | 0.88 | CHIT1 (0.35) | CHIT1CHIAHTR3ASCN9ADRD2 | |
| SCHEMBL15956253 | 0.85 | GRM5 (0.32) | CHIT1CHIASCN9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610258-B1 | Substituted piperidino dihydrothieno pyrimidines | BOEHRINGER INGELHEIM INT (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8754073-B2 | Substituted piperazino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-17 | — | — | US | disclosed |
| EP-2610258-A1 | Substituted piperidino dihydrothieno pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-03 | — | — | EP | disclosed |