Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 2/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 4/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088390 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL15088377 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL15800089 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL972213 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL12921440 | 1.00 | CHIT1 (0.35) | CHIT1CHIAHTR3APAK4PAK1 | |
| SCHEMBL12921348 | 0.91 | — | — | |
| SCHEMBL12948470 | 0.91 | — | — | |
| SCHEMBL12921347 | 0.91 | — | — | |
| SCHEMBL12210438 | 0.88 | CHIT1 (0.35) | CHIT1CHIAHTR3ASCN9ADRD2 | |
| SCHEMBL15956253 | 0.85 | GRM5 (0.32) | CHIT1CHIASCN9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754073-B2 | Substituted piperazino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-17 | — | — | US | disclosed |
| EP-2380891-A1 | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20110021501-A1 | SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021501-A1 | SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES | DPYD, P2RX1, P2RX5 | CHIT1 2457/4885CHIA 3035/4885HTR3A 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.