Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067065 | 0.84 | MEN1 (0.46) | MEN1KMT2ATNK2NPC1RAB9A | |
| SCHEMBL15068100 | 0.81 | MEN1 (0.45) | MEN1KMT2ATNK2HSD11B1NPC1 | |
| SCHEMBL8265696 | 0.80 | CA1 (0.43) | TNK2HIF1AHSD11B1 | |
| SCHEMBL1186911 | 0.76 | MEN1 (0.52) | MEN1KMT2ATNK2HSD11B1NPC1 | |
| SCHEMBL15067841 | 0.76 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15088638 | 0.74 | KMT2A (0.45) | MEN1KMT2ATNK2NPC1RAB9A | |
| SCHEMBL14184918 | 0.74 | CA1 (0.39) | TNK2HIF1AHSD11B1 | |
| SCHEMBL14184913 | 0.73 | HSD11B1 (0.37) | TNK2HIF1AHSD11B1NPC1RAB9A | |
| SCHEMBL21780925 | 0.73 | MEN1 (0.47) | MEN1KMT2AHSD11B1NPC1RAB9A | |
| SCHEMBL6922863 | 0.73 | HSD11B1 (0.40) | TNK2HIF1AHSD11B1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309211-B2 | Arylalkene derivatives and use thereof as selective estrogen receptor modulators | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2016-04-12 | — | — | US | disclosed |
| US-9309211-B2 | Arylalkene derivatives and use thereof as selective estrogen receptor modulators | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2016-04-12 | — | — | US | disclosed |
| US-9309211-B2 | Arylalkene derivatives and use thereof as selective estrogen receptor modulators | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2016-04-12 | — | — | US | disclosed |
| WO-2013097773-A1 | NOVEL ARYLALKENE DERIVATIVES AND USE THEREOF AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2013-07-04 | — | — | WO | disclosed |