Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 7/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030289 | 0.78 | CYP3A4 (0.38) | FDPSPGK1PGK2GGPS1 | |
| SCHEMBL7870277 | 0.77 | PGK1 (0.44) | FDPSPTPN5PGK1PGK2PTPN1 | |
| SCHEMBL17923941 | 0.76 | PGK1 (0.42) | FDPSPTPN5PGK1PGK2PTPN1 | |
| SCHEMBL11762641 | 0.76 | PTPN1 (0.52) | PGK1PGK2PTPN1 | |
| SCHEMBL1354398 | 0.76 | MEN1 (0.42) | PTPN5PGK1PGK2GGPS1 | |
| SCHEMBL17187126 | 0.75 | PDE2A (0.37) | PDE2AAKR1C3AKR1C2 | |
| SCHEMBL3390400 | 0.74 | PGK1 (0.52) | PTPN5PGK1PGK2PTPN1 | |
| SCHEMBL1338013 | 0.74 | PGK1 (0.44) | PTPN5PGK1PGK2GGPS1 | |
| SCHEMBL2028840 | 0.74 | LMNA (0.46) | PGK1 | |
| SCHEMBL23908217 | 0.73 | PGK1 (0.43) | FDPSPTPN5PGK1PGK2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |