Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798929 | 0.87 | CYP3A4 (0.42) | LMNACYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL8061160 | 0.84 | GPR35 (0.45) | LMNACYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL6017684 | 0.82 | GPR35 (0.37) | LMNACYP3A4HTTALDH1A1GAA | |
| SCHEMBL6017682 | 0.82 | GPR35 (0.37) | LMNACYP3A4HTTALDH1A1GAA | |
| SCHEMBL2032819 | 0.81 | ALDH1A1 (0.42) | LMNACYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL2030289 | 0.77 | CYP3A4 (0.38) | CYP3A4CYP2D6ALDH1A1HPGDTSHR | |
| SCHEMBL78562 | 0.76 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1MAPK1CA1 | |
| SCHEMBL2037217 | 0.74 | PTPRC (0.65) | LMNACYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL18562544 | 0.74 | TSHR (0.55) | LMNACYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL1509010 | 0.74 | FDPS (0.36) | PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20110136764-A1 | AMINO PYRIMIDINE ANTICANCER COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | LMNA 1103/4885CYP1A2 518/4885CYP3A4 161/4885 |
| US-20110136764-A1 | AMINO PYRIMIDINE ANTICANCER COMPOUNDS | DPYD, PTK2, TYMS | LMNA 4131/4885CYP1A2 3957/4885CYP3A4 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.