Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509102 | 0.84 | TAAR1 (0.30) | — | |
| SCHEMBL1508741 | 0.83 | MDM2 (0.36) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7921145 | 0.83 | MDM2 (0.36) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1508874 | 0.75 | KCNQ3 (0.39) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL14793575 | 0.75 | KMT2A (0.33) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL14817142 | 0.75 | KMT2A (0.33) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1508733 | 0.73 | KMO (0.32) | — | |
| SCHEMBL1508742 | 0.73 | KCNQ3 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1508739 | 0.73 | KCNQ3 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1509104 | 0.73 | TAAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |