SCHEMBL1509102

SCHEMBL1509102

Cc1cc(Cl)ccc1[C@@H]1NS(=O)(=O)N[C@]1(C)c1ccc(Cl)nc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1509104 0.89 TAAR1 (0.30) TAAR1
SCHEMBL1509100 0.89 TAAR1 (0.30) TAAR1
SCHEMBL1509045 0.84 KCNQ3 (0.31)
SCHEMBL14817142 0.82 KMT2A (0.33)
SCHEMBL14793575 0.82 KMT2A (0.33)
SCHEMBL7921145 0.74 MDM2 (0.36)
SCHEMBL1508741 0.74 MDM2 (0.36)
SCHEMBL1508733 0.73 KMO (0.32) NPC1
SCHEMBL14793574 0.71 TP53 (0.31)
SCHEMBL1508874 0.71 KCNQ3 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2298778-A1 IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE Daiichi Sankyo Company, Limited (JP) 2011-03-23 EP disclosed