SCHEMBL62357

SCHEMBL62357

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541107 0.96 LMNA (0.39) LMNATHRB
SCHEMBL64875 0.92 LMNA (0.41) LMNATHRBCA2
SCHEMBL6278209 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL1169605 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL28699116 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL4937641 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
Perflisopent SCHEMBL1509322 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL28701223 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL7626574 0.88 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL1271519 0.88 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170334872-A1 SEMI-SYNTHESIS PROCEDURES TETRAPHASE PHARMACEUTICALS, INC. 2017-11-23 US claimed
EP-3209642-A1 SEMI-SYNTHESIS PROCEDURES Tetraphase Pharmaceuticals, Inc. (US) 2017-08-30 EP claimed
CN-107108472-A Semi-synthesis process 四相制药公司 2017-08-29 CN claimed
US-10618879-B2 Semi-synthesis procedures TETRAPHASE PHARMACEUTICALS, INC. (US) 2020-04-14 US disclosed
CN-107108472-B Semi-synthesis process 四相制药公司 2020-03-13 CN disclosed
US-20190210988-A1 SEMI-SYNTHESIS PROCEDURES TETRAPHASE PHARMACEUTICALS, INC. 2019-07-11 US disclosed
US-10087157-B2 Semi-synthesis procedures TETRAPHASE PHARMACEUTICALS, INC. (US) 2018-10-02 US disclosed
CN-108602995-A Flame-retardant polyolefin resin composition 株式会社艾迪科 2018-09-28 CN disclosed
EP-2993710-B1 ULTRAVIOLET LIGHT-EMITTING DEVICE SOKO KAGAKU CO LTD (JP) 2018-06-06 EP disclosed
US-9972758-B2 Ultraviolet light emitting device SOKO KAGAKU CO., LTD. (JP) 2018-05-15 US disclosed
EP-2400515-B1 PROCESS FOR MANUFACTURING ELECTRET, AND ELECTROSTATIC INDUCTION-TYPE CONVERSION ELEMENT ASAHI GLASS CO LTD (JP) 2018-01-24 EP disclosed
US-7359118-B2 Method for producing mold for use in duplicating light diffusion sheet, light diffusion sheet and method for producing the same, and screen SONY CORPORATION (JP) 2008-04-15 US disclosed
US-20060103929-A1 Screen and its manufacturing method SONY CORPORATION (JP) 2006-05-18 US disclosed
EP-1630596-A1 SCREEN AND ITS MANUFACTURING METHOD Sony Corporation (JP) 2006-03-01 EP disclosed
US-20050184412-A1 Method for producing mold for use in duplicating light diffusion sheet, light diffusion sheet and method for producing the same, and screen SONY CORPORATION (JP) 2005-08-25 US disclosed
EP-1564587-A1 Method for producing mold for use in duplicating light diffusion sheet, light diffusion sheet and method for producing the same, and screen SONY CORPORATION (JP) 2005-08-17 EP disclosed
US-RE37022-E1 A FLUORINE CONTAINING POLYMER COMPRISING A POLYMER HAVING A FUNCTIONAL GROUP AND A FLUORINE-CONTAINING ALIPHATIC CYCLIC STRUCTURE DISSOLVED IN A SOLVENT MIXTURE OF AN APROTIC AND PROTIC FLUORINE-CONTAINING SOLVENTS ASAHI GLASS COMPANY LTD. (JP) 2001-01-16 US disclosed
US-5498657-A ALIPHATIC CYCLIC STRUCTURE ASAHI GLASS COMPANY LTD. (JP) 1996-03-12 US disclosed
US-5318996-A Blowing with mixture of water, chlorodifluoromethane dichlorofluoroethane and perfluorinated hydrocarbons BASF CORPORATION (US) 1994-06-07 US disclosed
WO-1993005200-A1 AZEOTROPE-LIKE COMPOSITIONS OF 1,1-DICHLORO-1-FLUOROETHANE AND PERFLUOROCARBONS AND OPTIONALLY NITROMETHANE ALLIED-SIGNAL INC. (US) 1993-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334872-A1 SEMI-SYNTHESIS PROCEDURES F7, CASP7, TCF7 LMNA 1054/4885THRB 803/4885CA2 1279/4885
US-20190210988-A1 SEMI-SYNTHESIS PROCEDURES F7, TET3, CASP7 LMNA 1543/4885THRB 1428/4885CA2 1058/4885
US-10087157-B2 Semi-synthesis procedures F7, CASP7, TCF7 LMNA 1132/4885THRB 784/4885CA2 1385/4885
US-10618879-B2 Semi-synthesis procedures F7, TET3, CASP7 LMNA 1543/4885THRB 1428/4885CA2 1058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.