Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244694 | 0.81 | MAPT (0.41) | LMNAKDM4EPOLBCASP6TSHR | |
| Bromide SCHEMBL15093306 | 0.79 | MAPT (0.40) | LMNAKDM4EPOLBCASP6TSHR | |
| SCHEMBL244724 | 0.75 | CYP1A2 (0.52) | LMNAKDM4EPOLBCASP6KMT2A | |
| SCHEMBL25105737 | 0.69 | CYP1A2 (0.52) | LMNAKDM4EPOLBCASP6KMT2A | |
| SCHEMBL244616 | 0.67 | MAPT (0.54) | LMNAKDM4EPOLBKMT2AOPRK1 | |
| SCHEMBL33808 | 0.67 | — | — | |
| SCHEMBL4357760 | 0.66 | ESR1 (0.56) | LMNAKDM4EPOLBCASP6KMT2A | |
| SCHEMBL11985971 | 0.66 | POLB (0.42) | LMNAKDM4EPOLBCASP6KMT2A | |
| SCHEMBL20021097 | 0.66 | MAPT (0.43) | LMNAKDM4EPOLBCASP6TSHR | |
| SCHEMBL1348618 | 0.65 | LMNA (0.73) | LMNAKDM4EPOLBCASP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013103724-A1 | 2- (TERT - BUTOXY) -2- (7 -METHYLQUINOLIN- 6 - YL) ACETIC ACID DERIVATIVES FOR TREATING AIDS | GILEAD SCIENCES, INC. (US) | 2013-07-11 | — | — | WO | disclosed |