SCHEMBL1509342

SCHEMBL1509342

CN(C)c1cccc2oc3cccc(N(C)C)c3c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
KDM4E B2RXH2 5/20 0.58
GAA P10253 5/20 0.58
ALDH1A1 P00352 4/20 0.42
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.36
NSD2 O96028 1/20 0.36
EGFR P00533 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PLEC Q15149 1/20 0.36
CHEK1 O14757 1/20 0.35
NEK2 P51955 1/20 0.35
LIMK1 P53667 1/20 0.35
DYRK1A Q13627 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745310 0.85 KDM4E (0.48) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL28347917 0.79 MAOA (0.57) MAPTKDM4EGAAALDH1A1SMN1; SMN2
SCHEMBL29693028 0.75 KDM4E (0.46) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL6285846 0.74 MAPT (1.00) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL28279 0.74 MAPT (1.00) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL29363940 0.74 MAPT (1.00) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL8114801 0.73 CA9 (0.50) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL4393558 0.73 GAA (0.51) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL3611550 0.72 EDNRA (0.59) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL8250952 0.72 KDR (0.50) MAPTKDM4EGAACHEK1LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361653-B2 Non-aqueous electrolyte secondary battery SHARP KABUSHIKI KAISHA (JP) 2013-01-29 US disclosed
US-20110052982-A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY SHARP KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed