SCHEMBL28279

SCHEMBL28279

CN(C)c1cccc2cccc(N(C)C)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
KDM4E B2RXH2 6/20 1.00
GAA P10253 5/20 1.00
MCL1 Q07820 1/20 0.47
ALDH1A1 P00352 9/20 0.45
TSHR P16473 5/20 0.45
HSD17B10 Q99714 5/20 0.45
HPGD P15428 4/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1B1 Q16678 1/20 0.45
SIGMAR1 Q99720 1/20 0.40
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
NSD2 O96028 2/20 0.39
LMNA P02545 2/20 0.39
MAPK1 P28482 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6285846 1.00 MAPT (1.00) MAPTKDM4EGAAMCL1ALDH1A1
SCHEMBL29363940 1.00 MAPT (1.00) MAPTKDM4EGAAMCL1ALDH1A1
Ammonia Solution, Strong SCHEMBL6838810 0.97 MAPT (0.95) MAPTKDM4EGAAMCL1ALDH1A1
Ammonia Solution, Strong SCHEMBL9336609 0.97 MAPT (0.95) MAPTKDM4EGAAMCL1ALDH1A1
Hydrochloric Acid SCHEMBL9815129 0.97 MAPT (0.95) MAPTKDM4EGAAMCL1ALDH1A1
SCHEMBL30833304 0.97 MAPT (0.95) MAPTKDM4EGAAMCL1ALDH1A1
SCHEMBL1509347 0.92 MAPT (0.85) MAPTKDM4EGAAMCL1ALDH1A1
N,N-Dimethylethanaminium SCHEMBL8487667 0.89 KDM4E (0.78) MAPTKDM4EGAAMCL1ALDH1A1
Formic Acid SCHEMBL7595259 0.87 MAPT (0.75) MAPTKDM4EGAAMCL1ALDH1A1
Phosphoric Acid SCHEMBL9139860 0.87 MAPT (0.75) MAPTKDM4EGAAMCL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11339 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060433-A Pressure-sensitive adhesive and preparation method and application thereof 南京大学 2026-05-19 CN claimed
US-12559514-B2 Synthesis of fluorinated nucleotides MERCK SHARP & DOHME LLC (US) 2026-02-24 US claimed
US-20260028308-A1 METHODS FOR MAKING AND USING ENDOXIFEN ATOSSA THERAPEUTICS INC (US) 2026-01-29 US claimed
US-20250382307-A1 IMPROVED METHODS FOR PREPARING N-METHYL ALANINE ESTERS OF MAYTANSINOL IMMUNOGEN, INC. 2025-12-18 US claimed
WO-2025222300-A1 ATRIAL NATRIURETIC PEPTIDE CONSTRUCTS FOR TARGETED PAYLOAD DELIVERY TO NPR-C EXPRESSING CELLS PROTEINQURE INC. (CA) 2025-10-30 WO claimed
US-20250250234-A1 FLUOROALCOHOLS AS CO-SOLVENTS FOR CHEMICAL SYNTHESIS AND METHODS FOR PRODUCING THE SAME UNIV MISSISSIPPI (US) 2025-08-07 US claimed
EP-4587445-A1 IMPROVED METHODS FOR PREPARING N-METHYL ALANINE ESTERS OF MAYTANSINOL ImmunoGen, Inc. (US) 2025-07-23 EP claimed
EP-4534652-A1 SPECIFIC T CELL FOR PREVENTING OR TREATING CANCER, AND PREPARATION METHOD THEREFOR Suzhou Ersheng Biopharmaceutical Co., Ltd. (CN) 2025-04-09 EP claimed
US-20240376037-A1 Process for the Production of Levulinic Acid and Derivatives Thereof UNIVERSITEIT ANTWERPEN (BE) 2024-11-14 US claimed
CN-110678462-B Isoindolinone inhibitors of MDM2-P53 interaction and methods of making the same 阿斯泰克斯治疗有限公司 2024-10-29 CN claimed
EP-0003258-B1 PREPARATION OF N-CHLOROIMIDES AND A NOVEL N-CHLOROIMIDE ELI LILLY AND COMPANY (US) 1982-01-13 EP claimed
US-4301312-A REACTING METHANOL WITH HYDROGEN AND CARBON MONOXIDE IN THE PRESENCE OF A TRANSITION METAL CARBONYL AND A TERTIARY AMINE SOLUTION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-11-17 US claimed
EP-0003258-A1 Preparation of N-chloroimides and a novel N-chloroimide ELI LILLY AND COMPANY (US) 1979-08-08 EP claimed
US-4163757-A ACIDIC CLAY CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-08-07 US claimed
US-4113282-A TETRANITRODIPHENYL ACETIC ACID DERIVATIVES THE MEAD CORPORATION (US) 1978-09-12 US claimed
US-4066641-A METHOD FOR CYCLIZATION TO GIVE CEPHEM RING HAMASHIMA YOSHIO 1978-01-03 US claimed
US-4029637-A FIBERS AKZONA INCORPORATED (US) 1977-06-14 US claimed
US-4010156-A Process for the rearrangement of penicillins to cephalosporins and intermediate compounds thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-01 US claimed
US-4005128-A FROM CARBON MONOXIDE AND ALCOHOL, METAL SALT CATALYST ATLANTIC RICHFIELD COMPANY (US) 1977-01-25 US claimed
US-3935012-A Photosensitive sheet materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-27 US claimed