SCHEMBL15093875

SCHEMBL15093875

O=C(O)CCc1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 1/20 0.48
▸ FFAR1 O14842 5/20 0.45
▸ THRA P10827 7/20 0.42
▸ THRB P10828 7/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.41
▸ PPARG P37231 1/20 0.40
▸ PTPRB P23467 1/20 0.40
▸ CDC25A P30304 1/20 0.40
▸ CDC25B P30305 1/20 0.40
▸ PTEN P60484 1/20 0.40
▸ PTPMT1 Q8WUK0 1/20 0.40
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ FFAR4 Q5NUL3 1/20 0.39
▸ ESR1 P03372 1/20 0.39
▸ NR3C1 P04150 1/20 0.39
▸ PGR P06401 1/20 0.39
▸ NR3C2 P08235 1/20 0.39
▸ AR P10275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31245820 0.83 KEAP1 (0.52) KEAP1FFAR1THRATHRBNPSR1
SCHEMBL15093745 0.81 KEAP1 (0.57) KEAP1FFAR1THRATHRBPPARG
SCHEMBL5670212 0.79 KEAP1 (0.64) KEAP1FFAR1THRATHRBNPSR1
SCHEMBL15093632 0.78 AKR1B1 (0.44) THRATHRBCA2
SCHEMBL15093932 0.77 NR4A2 (0.54) FFAR1
SCHEMBL12548984 0.75 KMT2A (0.36) NPSR1CDC25B
SCHEMBL28824891 0.75 GLRA1 (0.35) FFAR1THRATHRB
SCHEMBL1249170 0.74 KEAP1 (0.52) KEAP1FFAR1THRATHRBNPSR1
SCHEMBL28119178 0.74 AKR1B1 (0.44) THRATHRBCA2
Benzene SCHEMBL28576976 0.74 TDP1 (0.43) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232214-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2021-01-15 — — CN disclosed
EP-2776146-B1 METHOD OF PREPARATION OF A COMPOSITE POLYAMIDE MEMBRANE DDP SPECIALTY ELECTRONIC MAT US INC (US) 2020-05-13 — — EP disclosed
EP-2776146-B1 METHOD OF PREPARATION OF A COMPOSITE POLYAMIDE MEMBRANE DDP SPECIALTY ELECTRONIC MAT US INC (US) 2020-05-13 — — EP disclosed
CN-105848758-B Separation of hydrocarbons from aqueous mixtures using fouling resistant reverse osmosis membranes 陶氏环球技术有限责任公司 2020-01-17 — — CN disclosed
CN-105873666-B Composite polyamide membrane with high acid content and low azo content DOW GLOBAL TECHNOLOGIES LLC (US) 2019-11-01 — — CN disclosed
CN-106170333-B Composite polyamide membrane treated with dihydroxyaryl compound and nitrous acid 陶氏环球技术有限责任公司 2019-02-15 — — CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 — — CN disclosed
US-10137418-B2 Composite polyamide membrane made via interfacial polymerization using a blend of non-polar solvents DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-27 — — US disclosed
EP-3092057-B1 TREATMENT OF AQUEOUS MIXTURES CONTAINING ANIONIC SURFACTANTS USING FOULING RESISTANT REVERSE OSMOSIS MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-19 — — EP disclosed
EP-3092056-B1 DESALINATION OF AQUEOUS MIXTURE CONTAINING NANO-SIZED PARTICLES USING FOULING RESISTANT REVERSE OSMOSIS MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-01 — — EP disclosed
US-9073015-B2 Composite polyamide membrane DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-07 — — US disclosed
US-20140370191-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-18 — — US disclosed
US-20140370191-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-18 — — US disclosed
US-20140370191-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-18 — — US disclosed
EP-2776146-A1 COMPOSITE POLYAMIDE MEMBRANE Dow Global Technologies LLC (US) 2014-09-17 — — EP disclosed
WO-2014109946-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-17 — — WO disclosed
US-20140199483-A1 COMPOSITE POLYAMIDE MEMBRANE INCLUDING TRI-HYDROCARBYL PHOSPHATE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-17 — — US disclosed
WO-2014109945-A1 COMPOSITE POLYAMIDE MEMBRANE INCLUDING TRI-HYDROCARBYL PHOSPHATE DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-17 — — WO disclosed
WO-2013103666-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-11 — — WO disclosed
WO-2013103666-A1 COMPOSITE POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-11 — — WO disclosed
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