Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368908 | 0.70 | CALM1 (0.46) | CALM1BCL2BCL2L1TAAR1ALDH1A1 | |
| Diphenylmethane SCHEMBL28473853 | 0.67 | CALM1 (0.86) | CALM1BCL2BCL2L1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL28172316 | 0.66 | CALM1 (1.00) | CALM1BCL2BCL2L1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL14763944 | 0.66 | CALM1 (1.00) | CALM1BCL2BCL2L1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL4361124 | 0.66 | CALM1 (1.00) | CALM1BCL2BCL2L1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL3792579 | 0.66 | CALM1 (1.00) | CALM1BCL2BCL2L1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL1303 | 0.66 | CALM1 (1.00) | CALM1BCL2BCL2L1ALDH1A1LMNA | |
| SCHEMBL8650674 | 0.65 | CALM1 (0.46) | CALM1BCL2BCL2L1TAAR1ALDH1A1 | |
| SCHEMBL486262 | 0.65 | CALM1 (0.46) | CALM1BCL2BCL2L1TAAR1ALDH1A1 | |
| Diphenylmethane SCHEMBL25402252 | 0.64 | CALM1 (0.92) | CALM1BCL2BCL2L1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800738-A1 | HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE | Spinifex Pharmaceuticals Pty Ltd (AU) | 2014-11-12 | — | — | EP | disclosed |
| WO-2013102242-A1 | HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2013-07-11 | — | — | WO | disclosed |