Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094393 | 0.70 | CALM1 (0.46) | CALM1LMNABCL2BCL2L1TAAR1 | |
| SCHEMBL19100321 | 0.69 | KCNH2 (0.46) | LMNAALDH1A1CYP1A2TSHRRAB9A | |
| SCHEMBL8655842 | 0.67 | CALM1 (0.38) | CALM1LMNATAAR1ALDH1A1HRH3 | |
| Diphenylmethane SCHEMBL14763944 | 0.66 | CALM1 (1.00) | CALM1LMNAPLA2G10PLA2G2ABCL2 | |
| Diphenylmethane SCHEMBL28172316 | 0.66 | CALM1 (1.00) | CALM1LMNAPLA2G10PLA2G2ABCL2 | |
| Diphenylmethane SCHEMBL1303 | 0.66 | CALM1 (1.00) | CALM1LMNAPLA2G10PLA2G2ABCL2 | |
| Diphenylmethane SCHEMBL4361124 | 0.66 | CALM1 (1.00) | CALM1LMNAPLA2G10PLA2G2ABCL2 | |
| Diphenylmethane SCHEMBL3792579 | 0.66 | CALM1 (1.00) | CALM1LMNAPLA2G10PLA2G2ABCL2 | |
| SCHEMBL8650674 | 0.65 | CALM1 (0.46) | CALM1LMNABCL2BCL2L1TAAR1 | |
| SCHEMBL8610753 | 0.64 | CALM1 (0.44) | CALM1LMNABCL2BCL2L1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012375-A2 | SQUARATE KINASE INHIBITORS | WYETH (US) | 2009-01-22 | — | — | WO | claimed |
| EP-1637525-A1 | Benzoxazole compound, process for producing the same, and herbicides | Ube Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | claimed |
| US-20050233909-A1 | Benzoxazole compounds, process for producing the same and herbicides | UBE INDUSTRIES, LTD. (JP) | 2005-10-20 | — | — | US | claimed |
| US-20040014977-A1 | Benzoxazole compound, process for producing the same, and herbicide | KYOYU AGRI CO., LTD. (JP) | 2004-01-22 | — | — | US | claimed |
| CN-105131104-B | The reconstruct and sugar conjugation of peptide | 诺和诺德公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-103384661-B | Mineralocorticoid receptor antagonists | 默沙东公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-105131104-A | Remodeling and glycoconjugation of peptides | NOVO NORDISK AS | 2015-12-09 | — | — | CN | disclosed |
| CN-103384661-A | Mineralocorticoid receptor antagonists | MERCK SHARP & DOHME | 2013-11-06 | — | — | CN | disclosed |
| CN-1635901-B | Methods for reconstitution and glycoconjugation of peptides | NEOSE TECHNOLOGIES INC | 2012-03-28 | — | — | CN | disclosed |
| CN-102180944-A | Remodeling and glycoconjugation of peptides | NEOSE TECHNOLOGIES INC | 2011-09-14 | — | — | CN | disclosed |
| CN-101724075-A | Remodeling and glycoconjugation of peptides | NEOSE TECHNOLOGIES INC | 2010-06-09 | — | — | CN | disclosed |
| CN-100522988-C | Glycopegylation methods and proteins/peptides produced by the methods | NEOSE TECHNOLOGIES INC (DK) | 2009-08-05 | — | — | CN | disclosed |
| US-20020040002-A1 | Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor | ZENECA LIMITED | 2002-04-04 | — | — | US | disclosed |
| US-6242615-B1 | AMIDATION OF ACID CONTAINING COMPOUNDS; USEFUL IN INHIBITING TUMOR NECROSIS FACTOR AND METALLOPROTEINASES | ZENECA LIMITED (GB) | 2001-06-05 | — | — | US | disclosed |
| EP-0971881-A1 | PROCESS FOR THE PREPARATION OF N-(3-HYDROXY-SUCCINYL)-AMINO ACID DERIVATIVES | AstraZeneca AB (SE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998043946-A1 | PROCESS FOR THE PREPARATION OF N-(3-HYDROXY-SUCCINYL)-AMINO ACID DERIVATIVES | ZENECA LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |
| EP-0866367-A2 | Radiation sensitive composition | JSR Corporation (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-5652233-A | CARBAPENICILLINS | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5527791-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| US-5478820-A | Carbapenem deivatives; bactericides | ZENECA LTD. (GB) | 1995-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040002-A1 | Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor | MMP1, HCAR1, MMP13 | CALM1 3328/4885LMNA 1557/4885PLA2G10 2444/4885 |
| US-20050233909-A1 | Benzoxazole compounds, process for producing the same and herbicides | CBR3, CBR1, CYP4X1 | CALM1 796/4885LMNA 3101/4885PLA2G10 4829/4885 |
| US-20040014977-A1 | Benzoxazole compound, process for producing the same, and herbicide | CBR1, CBR3, CYP4X1 | CALM1 1649/4885LMNA 2248/4885PLA2G10 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.