Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.39 |
| ▸ | MGLL | Q99685 | 5/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094578 | 0.86 | MGLL (0.39) | FAAHABHD6MGLLPLA2G7CYP2D6 | |
| SCHEMBL15094637 | 0.82 | MGLL (0.46) | ABHD6MGLLPLA2G7ALDH1A1CYP2D6 | |
| SCHEMBL15094544 | 0.81 | RORC (0.43) | ABHD6MGLLPLA2G7 | |
| SCHEMBL15094825 | 0.80 | MGLL (0.55) | FAAHABHD6MGLLPLA2G7CYP2D6 | |
| SCHEMBL15094643 | 0.80 | MGLL (0.42) | FAAHABHD6MGLLPLA2G7NR1H2 | |
| Hydrochloric Acid SCHEMBL20167952 | 0.80 | MGLL (0.54) | FAAHABHD6MGLLPLA2G7CYP2D6 | |
| SCHEMBL15094559 | 0.78 | MGLL (0.46) | ABHD6MGLLPLA2G7MAPTALDH1A1 | |
| SCHEMBL15094475 | 0.78 | ABHD6 (0.39) | ABHD6MGLLPLA2G7 | |
| Fumaric Acid SCHEMBL20168297 | 0.77 | MGLL (0.51) | FAAHABHD6MGLLPLA2G7CYP2D6 | |
| SCHEMBL19260947 | 0.76 | MGLL (0.46) | ABHD6MGLLPLA2G7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800565-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2014-11-12 | — | — | EP | disclosed |
| WO-2013103973-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS (US) | 2013-07-11 | — | — | WO | disclosed |