Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628272 | 0.74 | BRD4 (0.49) | GAAMAPTCREBBPBRD4TDP1 | |
| SCHEMBL28784684 | 0.73 | MAPT (0.48) | GAAMAPTALDH1A1KCNH2 | |
| SCHEMBL27768409 | 0.71 | GAA (0.54) | GAAMAPTTDP1ALDH1A1 | |
| SCHEMBL27768438 | 0.70 | MAPT (0.53) | GAAMAPTCREBBP | |
| SCHEMBL13228878 | 0.69 | MAPT (0.49) | GAAMAPTCREBBPALDH1A1RXFP1 | |
| SCHEMBL12629105 | 0.68 | MAPT (0.47) | GAAMAPTALDH1A1RXFP1 | |
| SCHEMBL13229755 | 0.68 | S1PR5 (0.53) | GAAMAPTCREBBPBRD4 | |
| SCHEMBL12629101 | 0.67 | GAA (0.49) | GAAMAPT | |
| SCHEMBL27768522 | 0.67 | MAPT (0.49) | GAAMAPTCREBBPALDH1A1RXFP1 | |
| SCHEMBL27768506 | 0.67 | GAA (0.49) | GAAMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800738-A1 | HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE | Spinifex Pharmaceuticals Pty Ltd (AU) | 2014-11-12 | — | — | EP | disclosed |
| WO-2013102242-A1 | HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2013-07-11 | — | — | WO | disclosed |