Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.50 |
| ▸ | CTSS | P25774 | 6/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418094 | 0.96 | CTSK (0.47) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL4669748 | 0.83 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5258106 | 0.81 | MME (0.52) | CTSK | |
| SCHEMBL1835975 | 0.81 | MME (0.52) | CTSK | |
| SCHEMBL5934709 | 0.80 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL28139029 | 0.79 | CTSS (0.45) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL23423133 | 0.79 | BIRC2 (0.51) | CTSK | |
| SCHEMBL8139330 | 0.76 | CYP1A2 (0.50) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934902 | 0.76 | CTSK (0.70) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934832 | 0.76 | CTSK (0.70) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481499-B2 | Blockade of gamma-secretase activity to promote myelination by oligodendrocytes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |