Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | CTSL | P07711 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | FURIN | P09958 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316483 | 0.86 | CTSK (0.48) | CTSSCTSKCTSLCTSBANPEP | |
| SCHEMBL27668472 | 0.86 | LTA4H (0.45) | FURIN | |
| SCHEMBL30973589 | 0.85 | BCL9 (0.46) | — | |
| SCHEMBL28130928 | 0.80 | MMP2 (0.48) | CTSLCTSB | |
| SCHEMBL15095476 | 0.79 | CTSK (0.50) | CTSSCTSKCTSLCTSBANPEP | |
| SCHEMBL29250281 | 0.78 | BCL9 (0.38) | CTSL | |
| SCHEMBL28110893 | 0.78 | SLC1A3 (0.42) | FURIN | |
| SCHEMBL29569076 | 0.77 | MME (0.54) | CTSB | |
| SCHEMBL6657992 | 0.77 | ALDH1A1 (0.46) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL3495921 | 0.77 | ALDH1A1 (0.46) | CTSSCTSKCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755482-B | functionalized 9-bromo-camptothecin derivatives | 内尔维阿诺医学科学有限公司 | 2017-04-26 | — | — | CN | disclosed |