SCHEMBL15096024

SCHEMBL15096024

COc1ccc(C(c2ccc(Oc3cc(C)ccc3C(F)(F)F)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
RAB9A P51151 1/20 0.48
MAPT P10636 3/20 0.46
MAPK1 P28482 1/20 0.46
KDM4E B2RXH2 1/20 0.41
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
KCNH2 Q12809 1/20 0.40
ACHE P22303 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
EPHX2 P34913 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
KIF11 P52732 1/20 0.36
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15096015 0.89 L3MBTL1 (0.51) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL10001970 0.83 SLC6A4 (0.47) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL12277221 0.81 ACHE (0.54) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL12260130 0.81 ACHE (0.54) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL15096013 0.81 AR (0.55) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL9914241 0.79 ACHE (0.60) L3MBTL1RAB9AMAPTMAPK1ACHE
SCHEMBL15096012 0.78 AR (0.55) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL25986531 0.77 LTA4H (0.50) L3MBTL1RAB9AMAPTMAPK1KDM4E
SCHEMBL26037436 0.76 L3MBTL1 (0.43) ARL3MBTL1RAB9AMAPTMAPK1
SCHEMBL6061341 0.76 ACHE (0.47) ARL3MBTL1RAB9AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505962-B2 Adhesive composition containing resin having carbon-carbon multiple bond NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-11-29 US disclosed
US-20160311979-A1 COMPOSITION FOR FORMING PASSIVATION FILM, INCLUDING RESIN HAVING CARBON-CARBON MULTIPLE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-27 US disclosed
US-20140374887-A1 COMPOSITION FOR FORMING PASSIVATION FILM, INCLUDING RESIN HAVING CARBON-CARBON MULTIPLE BOND NISSAN CHEMICAL IMDUSTRIES, LTD. (JP) 2014-12-25 US disclosed
US-20130177763-A1 ADHESIVE COMPOSITION CONTAINING RESIN HAVING CARBON-CARBON MULTIPLE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-07-11 US disclosed