Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456470 | 0.82 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL3627757 | 0.80 | THRB (0.54) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL2150158 | 0.80 | CA12 (0.50) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL17226148 | 0.78 | CA12 (0.49) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL12532591 | 0.78 | NQO1 (0.56) | SMN1; SMN2TSHRHRH3 | |
| SCHEMBL8801453 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL9259951 | 0.77 | THRB (0.51) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| 1,4-Diallyloxybenzene SCHEMBL302448 | 0.77 | CA12 (0.63) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL7927491 | 0.77 | CA2 (0.47) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL7929787 | 0.76 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTUSP2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791876-B1 | Optical elements | OPHTHONIX INC (US) | 2013-07-10 | — | — | EP | disclosed |