Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371115 | 0.82 | MITF (0.40) | ALDH1A1MITFCYP2D6 | |
| SCHEMBL14565080 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2MGLLCHATMEN1 | |
| SCHEMBL6546259 | 0.80 | CHAT (0.47) | GABRA1GABRB2MGLLCHATMEN1 | |
| SCHEMBL3314625 | 0.80 | CHAT (0.47) | GABRA1GABRB2MGLLCHATMEN1 | |
| SCHEMBL1283641 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2MGLLCHATMEN1 | |
| SCHEMBL3864511 | 0.79 | TSHR (0.46) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL22401086 | 0.79 | CYP3A4 (0.47) | THRBMITFCYP2D6 | |
| SCHEMBL29897321 | 0.78 | LMNA (0.57) | GABRA1GABRB2MGLLMEN1LMNA | |
| SCHEMBL18242067 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2MGLLCHATMEN1 | |
| SCHEMBL2915753 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2MGLLCHATMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295592-B1 | An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | NIPPON CATALYTIC CHEM IND (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-1160329-B1 | An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | NIPPON CATALYTIC CHEM IND (JP) | 2011-04-06 | — | — | EP | disclosed |
| EP-2295592-A1 | An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | Nippon Shokubai Co., Ltd. (JP) | 2011-03-16 | — | — | EP | disclosed |
| EP-1160235-B1 | A method for producing alpha-hydroxycarboxylic acid | NIPPON CATALYTIC CHEM IND (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-7078225-B2 | Method for enzymatically producing an optically active cyanohydrin | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-07-18 | — | — | US | disclosed |
| EP-1043021-B1 | PURINE DERIVATIVES FOR THE TREATMENT OF ALLERGIC DISEASES AND SYSTEMIC LUPUS ERYTHEMATOSUS | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-0882727-B9 | NOVEL PURINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1527135-A1 | FLUORINATED POLYMERS | 3M Innovative Properties Company (US) | 2005-05-04 | — | — | EP | disclosed |
| US-20050089977-A1 | Enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | NIPPON SHOKUBAI CO., LTD. | 2005-04-28 | — | — | US | disclosed |
| US-6864389-B2 | Method for producing α-hydroxycarboxylic acid | NIPPON SHOKUBAI CO., LTD. (JP) | 2005-03-08 | — | — | US | disclosed |
| US-6376501-B1 | INHIBITING OR REGULATING IMMUNE RESPONSE USING PURINE-DERIVED COMPOUND; NON-STEROIDAL COMPOUND | JAPAN ENERGY CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| US-20020006646-A1 | Enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | NIPPON SHOKUBAI CO., LTD. | 2002-01-17 | — | — | US | disclosed |
| EP-1160329-A2 | An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin | Nippon Shokubai Co., Ltd. (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1160235-A2 | A method for producing alpha-hydroxycarboxylic acid | Nippon Shokubai Co., Ltd. (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1043021-A1 | TYPE 2 HELPER T CELL-SELECTIVE IMMUNE RESPONSE SUPPRESSORS | Japan Energy Corporation (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-6028076-A | FOR INDUCING .ALPHA.-INTERFERON IN A PATIENT HAVING HEPATITIS B OR C, BY ADMINISTERING PURINE DERIVATIVE | JAPAN ENERGY CORPORATION (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0882727-A1 | NOVEL PURINE DERIVATIVES | JAPAN ENERGY CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0549222-A2 | Siloxy-functional cyclopolysiloxanes | DOW CORNING CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |