Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15097502 | 0.83 | ESR1 (0.39) | TDP1ALDH1A1TXNRD1KCNH2GSR | |
| SCHEMBL15097498 | 0.77 | ALOX5 (0.44) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15097500 | 0.77 | ALOX5 (0.41) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11509569 | 0.77 | ALDH1A1 (0.65) | TDP1ALDH1A1TXNRD1KCNH2MEN1 | |
| SCHEMBL15097487 | 0.77 | ALOX5 (0.38) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11602247 | 0.75 | VCAM1 (0.53) | TDP1ALDH1A1ESR1KMT2AMAPT | |
| SCHEMBL15097510 | 0.74 | AR (0.43) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15097488 | 0.74 | S1PR1 (0.43) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL16519848 | 0.74 | ALDH1A1 (0.53) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7998324 | 0.73 | VCAM1 (0.54) | TDP1ALDH1A1ESR1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130177851-A1 | PHOTORESIST COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-11 | — | — | US | disclosed |