Deferoxamine

Deferoxamine

SCHEMBL1509901

CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.[Fe]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 8/20 0.97
HIF1A Q16665 1/20 0.97
TET2 Q6N021 1/20 0.97
DOHH Q9BU89 1/20 0.97
KDM4E B2RXH2 1/20 0.90
LMNA P02545 1/20 0.90
GAA P10253 1/20 0.90
SMN1; SMN2 Q16637 1/20 0.90
PAOX Q6QHF9 3/20 0.45
SLC6A5 Q9Y345 2/20 0.43
KDM4C Q9H3R0 7/20 0.39
CASP2 P42575 1/20 0.37
KDM5A P29375 1/20 0.36
KDM7A Q6ZMT4 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
NAAA Q02083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21051754 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
SCHEMBL26511991 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
SCHEMBL13367139 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
SCHEMBL17109729 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
SCHEMBL19040665 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
Deferoxamine SCHEMBL10498260 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
SCHEMBL17100575 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
Deferoxamine SCHEMBL34571 0.99 KDM4A (1.00) KDM4AHIF1ATET2DOHHKDM4E
Deferoxamine SCHEMBL20658960 0.97 KDM4A (0.97) KDM4AHIF1ATET2DOHHKDM4E
Deferoxamine SCHEMBL20658962 0.97 KDM4A (0.97) KDM4AHIF1ATET2DOHHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060120980-A1 Novel dermatological composition using bio-activating organocatalysts EBERSYTES, LLC 2006-06-08 US claimed
EP-1648376-A2 NOVEL DERMATOLOGICAL COMPOSITION Ebersytes, LLC (US) 2006-04-26 EP claimed
EP-1530720-A4 BREAST CANCER ERADICATION PROGRAM SIRBASKU DAVID A (US) 2005-08-31 EP claimed
EP-1530720-A2 BREAST CANCER ERADICATION PROGRAM Sirbasku, David A. (US) 2005-05-18 EP claimed
WO-2005000224-A2 NOVEL DERMATOLOGICAL COMPOSITION EBERSYTES, LLC (US) 2005-01-06 WO claimed
US-20040247633-A1 Novel dermatological composition EBERSYTES, LLC 2004-12-09 US claimed
WO-2003042404-A2 BREAST CANCER ERADICATION PROGRAM SIRBASKU DAVID A (US) 2003-05-22 WO claimed
US-20030072812-A1 Breast cancer eradication program SIGNE BIOPHARMA INC. 2003-04-17 US claimed
US-20250037787-A1 CONCENTRATION BOUNDS IN LARGE NETWORKS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-30 US disclosed
US-20230158177-A1 HYPOXIA-TARGETING CONTRAST AGENT AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-05-25 US disclosed
CN-114349801-B Technetium-99 m labeled isopenitrile-containing fenoxamine derivative, and preparation method and application thereof 北京师范大学 2023-03-24 CN disclosed
CN-114349801-A Technetium-99 m labeled isopenitrile-containing fenoxamine derivative, and preparation method and application thereof 北京师范大学 2022-04-15 CN disclosed
EP-3105198-B1 SOIL BACTERIA FOR INOCULATING STRESS SOILS BIOFIL MIKROBIOLOGIAI GENTECHNOLOGIAI ES BIOKEMIAI KFT (HU) 2022-02-16 EP disclosed
CN-107281498-A Iron ion chelating agent modified by polyethylene glycol 四川大学华西医院 2017-10-24 CN disclosed
US-20040247633-A1 Novel dermatological composition EBERSYTES, LLC 2004-12-09 US disclosed
CN-1331971-A New application of deferiprone APTEX INC (CA) 2002-01-23 CN disclosed
EP-0553273-A4 POLYMER-DEFEROXAMINE-FERRIC IRON ADDUCTS FOR USE IN MAGNETIC RESONANCE IMAGING BIOMED FRONTIERS INC (US) 1998-04-22 EP disclosed
US-5268165-A Administering a diagnostic contrast agent BIOMEDICAL FRONTIERS, INC. (US) 1993-12-07 US disclosed
EP-0553273-A1 POLYMER-DEFEROXAMINE-FERRIC IRON ADDUCTS FOR USE IN MAGNETIC RESONANCE IMAGING BIOMEDICAL FRONTIERS, INC. (US) 1993-08-04 EP disclosed
WO-1992007259-A1 POLYMER-DEFEROXAMINE-FERRIC IRON ADDUCTS FOR USE IN MAGNETIC RESONANCE IMAGING BIOMEDICAL FRONTIERS, INC. (US) 1992-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060120980-A1 Novel dermatological composition using bio-activating organocatalysts FGF1, FGF2, FGFR3 KDM4A 3738/4885HIF1A 2713/4885TET2 3573/4885
US-20230158177-A1 HYPOXIA-TARGETING CONTRAST AGENT AND METHODS OF USE THEREOF HIF1AN, HIF1A, HYOU1 KDM4A 2855/4885HIF1A 2/4885TET2 4017/4885
US-20040247633-A1 Novel dermatological composition FGF2, FGF1, KRT18 KDM4A 3316/4885HIF1A 1762/4885TET2 2328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.