Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905682 | 0.96 | TSHR (0.37) | PTGER2PTGER3TSHRVCAM1 | |
| SCHEMBL208988 | 0.81 | TSHR (0.36) | TSHRPRKCAMEN1GAAKMT2A | |
| SCHEMBL23111823 | 0.81 | TSHR (0.35) | PTGER2TBXA2RTSHRPRKCAMEN1 | |
| SCHEMBL13650694 | 0.79 | MT-CO2 (0.31) | — | |
| SCHEMBL4969197 | 0.79 | TSHR (0.33) | PTGER2TBXA2RTSHRPRKCAMEN1 | |
| SCHEMBL8379082 | 0.79 | FAAH (0.36) | PTGER2PTGER3TSHRPRKCAMEN1 | |
| SCHEMBL13990672 | 0.76 | MEN1 (0.32) | TSHRMEN1GAAKMT2ALMNA | |
| SCHEMBL2725347 | 0.76 | MEN1 (0.32) | PTGER2PTGER3TBXA2RTSHRMEN1 | |
| SCHEMBL1580301 | 0.76 | MEN1 (0.32) | PTGER2PTGER3TBXA2RTSHRMEN1 | |
| SCHEMBL9443639 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292653-B1 | Novel insulin derivatives | NOVO NORDISK AS (DK) | 2014-05-21 | — | — | EP | disclosed |
| EP-2292653-A1 | Novel insulin derivatives | Novo Nordisk A/S (DK) | 2011-03-09 | — | — | EP | disclosed |