SCHEMBL208988

SCHEMBL208988

CC1CC(=O)N(OC(=O)CCCCC(=O)O)C1=O

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.34
ABL1 P00519 1/20 0.33
IDE P14735 1/20 0.33
PPARG P37231 1/20 0.33
RIN1 Q13671 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
LMNA P02545 2/20 0.32
PRKCA P17252 5/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
FAAH O00519 3/20 0.32
ALDH1A1 P00352 1/20 0.32
AKR1B1 P15121 1/20 0.32
NFKB1 P19838 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208987 0.94 PRKCA (0.35) PRKCAGAAKMT2AFAAHALDH1A1
SCHEMBL17035700 0.87 PRKCA (0.34) PRKCAKMT2A
SCHEMBL29293697 0.87 PRKCA (0.38) PRKCAMEN1KMT2A
SCHEMBL4969197 0.84 TSHR (0.33) TSHRLMNAPRKCAMEN1GAA
SCHEMBL20375257 0.83 FKBP1A (0.39) MEN1GAAKMT2AALDH1A1
SCHEMBL23111823 0.82 TSHR (0.35) TSHRLMNAPRKCAMEN1GAA
SCHEMBL26263126 0.82 TBXAS1 (0.30) TSHRMEN1KMT2A
SCHEMBL16790693 0.81 PRKCA (0.31) PRKCA
SCHEMBL12457816 0.81 FAAH (0.32) FAAH
SCHEMBL8379082 0.81 FAAH (0.36) TSHRPRKCAMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006073465-A2 MODIFIED MICROSURFACES AND METHODS OF THEIR MANUFACTURE PROTIVERIS, INC. (US) 2006-07-13 WO claimed
US-20050260423-A1 Modified microsurfaces and methods of their manufacture PROTIVERIS, INC. 2005-11-24 US claimed
US-8088753-B2 Heparin conjugates and methods MEDIPLEX CORPORATION, KOREA (KR) 2012-01-03 US disclosed
EP-2173359-A2 HEPARIN CONJUGATES AND METHODS Mediplex Corp. (KR) 2010-04-14 EP disclosed
US-20090149424-A1 HEPARIN CONJUGATES AND METHODS MEDIPLEX CORPORATION, KOREA (KR) 2009-06-11 US disclosed
WO-2009005258-A2 HEPARIN CONJUGATES AND METHODS MEDIPLEX CORP. (KR) 2009-01-08 WO disclosed
EP-1721603-A1 Nanoparticles for bioconjugation Albert-Ludwigs-Universität Freiburg (DE) 2006-11-15 EP disclosed
WO-2006073465-A2 MODIFIED MICROSURFACES AND METHODS OF THEIR MANUFACTURE PROTIVERIS, INC. (US) 2006-07-13 WO disclosed
US-20050260423-A1 Modified microsurfaces and methods of their manufacture PROTIVERIS, INC. 2005-11-24 US disclosed
EP-1111069-A1 Modified nucleic acids and their use BioChip Technologies GmbH (DE) 2001-06-27 EP disclosed