Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5881114 | 0.85 | HPGD (0.55) | HPGDTSHRRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL2854732 | 0.84 | HTT (0.49) | HPGDTSHRRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7934151 | 0.84 | ALDH1A1 (0.45) | HPGDTSHRKDM1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL1311491 | 0.83 | SMN1; SMN2 (0.49) | HPGDTSHRRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL18718210 | 0.83 | TSHR (0.44) | HPGDTSHRKDM1ARAB9ASMN1; SMN2 | |
| SCHEMBL6687682 | 0.82 | SMN1; SMN2 (0.50) | HPGDRAB9AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL15677337 | 0.82 | KDM4E (0.42) | L3MBTL1SMN1; SMN2GAAALDH1A1AAK1 | |
| SCHEMBL31096231 | 0.81 | TSHR (0.56) | HPGDTSHRRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL182753 | 0.81 | TSHR (0.56) | HPGDTSHRRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL578735 | 0.81 | L3MBTL1 (0.43) | TSHRL3MBTL1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315502-B1 | C,O-SPIRO ARYL GLYCOSIDE COMPOUNDS, PREPARATION THEREFOR AND USE THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2024-07-31 | — | — | EP | disclosed |
| CN-112300115-B | Liquid crystal compound, liquid crystal composition, liquid crystal display element and liquid crystal display | 石家庄诚志永华显示材料有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-110499161-B | Liquid crystal compound, liquid crystal composition and liquid crystal display device | 石家庄诚志永华显示材料有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3912977-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | BioMarin Pharmaceutical Inc. (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-3046920-B1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARM INC (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-112980458-A | Bridge-ring alkane-containing liquid crystal compound and preparation method and application thereof | 北京八亿时空液晶科技股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-109207160-B | Liquid crystal compound with negative dielectric anisotropy as well as preparation method and application thereof | 北京八亿时空液晶科技股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112300115-A | Liquid crystal compound, liquid crystal composition, liquid crystal display element and liquid crystal display | 石家庄诚志永华显示材料有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-02-04 | — | — | US | disclosed |
| US-20180305390-A1 | C,O-SPIRO ARYL GLYCOSIDE COMPOUNDS, PREPARATION THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2018-10-25 | — | — | US | disclosed |
| WO-2002079344-A1 | FLUORINATED FLUORENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-10 | — | — | WO | disclosed |
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| CN-1019109-B | The insect-killing composition that contains diphenyl ether derivatives pesticide compound | ICI PLC (GB) | 1992-11-18 | — | — | CN | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305390-A1 | C,O-SPIRO ARYL GLYCOSIDE COMPOUNDS, PREPARATION THEREFOR AND USE THEREOF | SLC5A2, SLC5A1, GLP1R | HPGD 2043/4885TSHR 2919/4885KDM1A 3464/4885 |
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SLC5A2, SLC5A1, GLP1R | HPGD 2043/4885TSHR 2919/4885KDM1A 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.