Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | CNR1 | P21554 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | PKLR | P30613 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711333 | 0.88 | LMNA (0.69) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL18701978 | 0.86 | LMNA (0.66) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL28819244 | 0.85 | LMNA (0.65) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL2312877 | 0.83 | LMNA (0.62) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL1945062 | 0.83 | L3MBTL1 (0.80) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL27370216 | 0.83 | HTT (0.70) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL4265072 | 0.82 | CACNA2D1 (0.65) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL4274513 | 0.82 | CNR1 (1.00) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL15100856 | 0.82 | LMNA (0.61) | LMNACNR1HTTGAASMN1; SMN2 | |
| SCHEMBL4963231 | 0.82 | CNR1 (0.66) | LMNACNR1HTTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013103973-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS (US) | 2013-07-11 | — | — | WO | disclosed |