Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15106914 | 0.66 | TLR8 (0.45) | TLR8BRD4BRD2 | |
| Hydrochloric Acid SCHEMBL15106897 | 0.66 | TLR8 (0.36) | TLR8BRD4BRD2 | |
| SCHEMBL5366242 | 0.63 | DDB1 (0.44) | GAASMN1; SMN2 | |
| SCHEMBL30132395 | 0.62 | SCN9A (0.36) | TLR8LMNABRD4BRD2 | |
| SCHEMBL27542205 | 0.61 | ALDH1A1 (0.45) | LMNAGAASMN1; SMN2BRD4BRD2 | |
| SCHEMBL12987163 | 0.60 | ALDH1A1 (0.36) | LMNAGAASMN1; SMN2BRD4BRD2 | |
| SCHEMBL5366019 | 0.60 | — | — | |
| SCHEMBL70884 | 0.58 | — | — | |
| SCHEMBL30883036 | 0.58 | CYP1A2 (0.49) | LMNABRD4BRD2 | |
| Hydrochloric Acid SCHEMBL14912306 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130183252-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME | SENOMYX, INC. (US) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183252-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME | TAS2R50, TAS2R1, TAS2R5 | TLR8 3044/4885DYRK1A 666/4885LMNA 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.