Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 11/20 | 0.41 |
| ▸ | BRD2 | P25440 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800965 | 0.70 | TLR8 (0.40) | TLR8BRD4BRD2CYP1A2USP2 | |
| SCHEMBL15815057 | 0.67 | AURKA (0.50) | BRD4BRD2JAK2CREBBPATAD2 | |
| Hydrochloric Acid SCHEMBL15106898 | 0.67 | TLR8 (0.43) | TLR8BRD4BRD2CYP1A2ALDH1A1 | |
| SCHEMBL13982304 | 0.66 | CYP1A2 (0.43) | TLR8BRD4BRD2CYP1A2ALDH1A1 | |
| SCHEMBL15106910 | 0.66 | TLR8 (0.33) | TLR8BRD4BRD2 | |
| SCHEMBL5366019 | 0.64 | — | — | |
| SCHEMBL30420643 | 0.63 | BRD4 (0.42) | BRD4BRD2CYP1A2USP2JAK2 | |
| SCHEMBL12800390 | 0.63 | BRD4 (0.43) | BRD4BRD2JAK2CREBBPTDO2 | |
| SCHEMBL12427192 | 0.63 | CYP1A2 (0.51) | TLR8BRD4BRD2CYP1A2USP2 | |
| SCHEMBL29836739 | 0.63 | BRD4 (0.46) | TLR8BRD4BRD2CYP1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130183252-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME | SENOMYX, INC. (US) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183252-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME | TAS2R50, TAS2R1, TAS2R5 | TLR8 3044/4885BRD4 1044/4885BRD2 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.