Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046538 | 0.94 | MAPK1 (0.32) | EHMT2EHMT1MAPK1 | |
| SCHEMBL12879597 | 0.89 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL12879590 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL15106978 | 0.81 | MGAT2 (0.36) | EHMT2EHMT1 | |
| SCHEMBL12879610 | 0.81 | KDM4E (0.33) | — | |
| SCHEMBL12879987 | 0.79 | TACR3 (0.35) | — | |
| SCHEMBL8059113 | 0.79 | TACR3 (0.35) | — | |
| SCHEMBL12879611 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL8062312 | 0.77 | HTR6 (0.33) | MAPK1 | |
| SCHEMBL8038226 | 0.77 | AKR1C3 (0.42) | EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090626-B2 | Piperazino-dihydrothienopyrimidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20130274264-A1 | PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-17 | — | — | US | disclosed |
| US-8486948-B2 | Piperazinodihydrothienopyrimidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274264-A1 | PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES | PDE4A, PDE12, PDE4B | EHMT2 2556/4885EHMT1 2739/4885MAPK1 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.