Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685946 | 0.88 | ACMSD (0.64) | APPHSD17B1HSD17B2ESR2ALOX5AP | |
| SCHEMBL9181957 | 0.88 | ESR2 (0.53) | APPHSD17B1HSD17B2ESR2ALOX5AP | |
| SCHEMBL22381411 | 0.86 | FEN1 (0.59) | APPHSD17B1HSD17B2ESR2ALOX5AP | |
| SCHEMBL27515405 | 0.82 | HPGD (0.63) | HSD17B1HSD17B2ESR2ALOX5APFEN1 | |
| SCHEMBL21113986 | 0.82 | ALOX5AP (0.49) | APPHSD17B1HSD17B2ESR2ALOX5AP | |
| SCHEMBL31589709 | 0.81 | ALDH1A1 (0.54) | APPHSD17B1HSD17B2ESR2ALOX5AP | |
| SCHEMBL28742545 | 0.80 | APP (0.82) | APPESR2HSD17B10ALDH1A1HPGD | |
| SCHEMBL13978633 | 0.80 | HSD17B1 (0.55) | APPHSD17B1HSD17B2ESR2HSD17B10 | |
| SCHEMBL857363 | 0.79 | ESR1 (0.68) | APPHSD17B1HSD17B2ESR2HSD17B10 | |
| SCHEMBL30635318 | 0.79 | ESR1 (0.68) | APPHSD17B1HSD17B2ESR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013105753-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AND METHODS FOR PREPARING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2013-07-18 | — | — | WO | disclosed |