Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 19/20 | 0.76 |
| ▸ | THRA | P10827 | 17/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887024 | 0.93 | THRB (0.86) | THRBTHRAPPARG | |
| SCHEMBL4897968 | 0.86 | THRB (1.00) | THRBTHRAPPARG | |
| SCHEMBL3655263 | 0.84 | THRB (0.54) | THRBTHRAMEN1KMT2A | |
| SCHEMBL3661614 | 0.77 | THRB (0.56) | THRBTHRA | |
| SCHEMBL10940612 | 0.75 | KMO (0.53) | THRBTHRAPPARG | |
| SCHEMBL3680135 | 0.74 | THRA (0.65) | THRBTHRAMEN1KMT2A | |
| SCHEMBL15111384 | 0.74 | APP (0.46) | THRBTHRAMEN1KMT2A | |
| SCHEMBL15112620 | 0.74 | APP (0.50) | THRBTHRAMEN1KMT2A | |
| SCHEMBL4896502 | 0.73 | THRB (1.00) | THRBTHRA | |
| SCHEMBL8033396 | 0.72 | APP (0.63) | THRBTHRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013106328-A1 | TETRASUBSTITUTED BENZENES FOR TREATMENT OF EARLY ONSET ALZHEIMER'S DISEASE | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-18 | — | — | WO | disclosed |