Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CLK1 | P49759 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | WNT3A | P56704 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489036 | 0.92 | CSNK1D (0.70) | CSNK1DMEN1ALDH1A1HTTCLK1 | |
| SCHEMBL18250790 | 0.90 | MAPT (0.80) | CSNK1DMEN1ALDH1A1HTTCLK1 | |
| SCHEMBL15112849 | 0.88 | CSNK1D (0.70) | CSNK1DMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL15113372 | 0.88 | CSNK1D (0.81) | CSNK1DCLK1WNT3AMAPTGAA | |
| SCHEMBL15113374 | 0.88 | GAA (0.64) | CSNK1DMEN1KMT2AMAPTGAA | |
| SCHEMBL17410545 | 0.87 | GAA (0.64) | CSNK1DWNT3AMAPTGAALMNA | |
| SCHEMBL15112843 | 0.87 | CSNK1D (0.71) | CSNK1DMAPTGAALMNAPOLB | |
| SCHEMBL15112848 | 0.85 | LMNA (0.62) | CSNK1DMEN1KMT2AMAPTGAA | |
| SCHEMBL17287808 | 0.84 | CSNK1D (1.00) | CSNK1DKMT2AWNT3AMAPTLMNA | |
| SCHEMBL15112845 | 0.84 | KMT2A (0.66) | CSNK1DMEN1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018280-B2 | Method for freezing aggregates of pluripotent stem cell-derived cardiomyocytes | KYOTO UNIVERSITY (JP) | 2024-06-25 | — | — | US | disclosed |
| US-20200325448-A1 | METHOD FOR FREEZING AGGREGATES OF PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES | KYOTO UNIVERSITY (JP) | 2020-10-15 | — | — | US | disclosed |
| US-10233426-B2 | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds | KYOTO UNIVERSITY (JP) | 2019-03-19 | — | — | US | disclosed |
| US-10196609-B2 | Composition for promoting cardiac differentiation of pluripotent stem cell comprising EGFR inhibitor | KYOTO UNIVERSITY (JP) | 2019-02-05 | — | — | US | disclosed |
| US-20170152485-A1 | Method for Inducing Cardiac Differentiation of Pluripotent Stem Cell with Low-Molecular Compounds | KYOTO UNIVERSITY (JP) | 2017-06-01 | — | — | US | disclosed |
| US-20170152485-A1 | Method for Inducing Cardiac Differentiation of Pluripotent Stem Cell with Low-Molecular Compounds | KYOTO UNIVERSITY (JP) | 2017-06-01 | — | — | US | disclosed |
| US-9587220-B2 | Method for inducing cardiac differentiation of pluripotent stem cell | KYOTO UNIVERSITY (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9587220-B2 | Method for inducing cardiac differentiation of pluripotent stem cell | KYOTO UNIVERSITY (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9499790-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20160002600-A1 | COMPOSITION FOR PROMOTING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL COMPRISING EGFR INHIBITOR | KYOTO UNIVERSITY (JP) | 2016-01-07 | — | — | US | disclosed |
| US-20160002600-A1 | COMPOSITION FOR PROMOTING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL COMPRISING EGFR INHIBITOR | KYOTO UNIVERSITY (JP) | 2016-01-07 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233426-B2 | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds | SRC, MYLK2, YES1 | CSNK1D 207/4885MEN1 4877/4885ALDH1A1 2969/4885 |
| US-20200325448-A1 | METHOD FOR FREEZING AGGREGATES OF PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES | TNNI3, MYLK2, TNNT2 | CSNK1D 2247/4885MEN1 4814/4885ALDH1A1 442/4885 |
| US-12018280-B2 | Method for freezing aggregates of pluripotent stem cell-derived cardiomyocytes | TNNI3, MYLK2, TNNT2 | CSNK1D 2247/4885MEN1 4814/4885ALDH1A1 442/4885 |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | TNNI3, MYLK2, TNNT2 | CSNK1D 1539/4885MEN1 4824/4885ALDH1A1 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.