SCHEMBL15134131

SCHEMBL15134131

CCCCCCCCCCC(O)CN(CCCCN(CCCC)CC(C)O)CCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 5/20 0.39
PLA2G1B P04054 3/20 0.39
PLA2G2A P14555 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
FFAR1 O14842 1/20 0.38
PSMD14 O00487 2/20 0.37
MMP2 P08253 2/20 0.37
ATG4B Q9Y4P1 2/20 0.37
HSP90AA1 P07900 1/20 0.37
RAD52 P43351 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SPHK1 Q9NYA1 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22354526 0.94 GPR84 (0.37) GPR84PLA2G1BPLA2G2AKDM4EMAPK1
SCHEMBL18789543 0.93 GPR84 (0.43) GPR84PLA2G1BPLA2G2AKDM4EMAPK1
SCHEMBL25742709 0.92 PLA2G1B (0.45) GPR84PLA2G1BPLA2G2AKDM4EMAPK1
SCHEMBL12977494 0.89 GPR84 (0.40) GPR84PLA2G1BPLA2G2AFFAR4FFAR1
SCHEMBL20717745 0.88 GPR84 (0.40) GPR84PLA2G1BPLA2G2AFFAR4FFAR1
SCHEMBL17199810 0.88 GPR84 (0.47) GPR84PLA2G1BPLA2G2AFFAR4FFAR1
SCHEMBL3531190 0.88 GPR84 (0.47) GPR84PLA2G1BPLA2G2AKDM4EMAPK1
SCHEMBL3540872 0.88 GPR84 (0.47) GPR84PLA2G1BPLA2G2AKDM4EMAPK1
SCHEMBL11611967 0.88 GPR84 (0.47) GPR84PLA2G1BPLA2G2AKDM4EMAPK1
SCHEMBL26039947 0.88 GPR84 (0.47) GPR84PLA2G1BPLA2G2AKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150140107-A1 DELIVERY OF HYDROPHOBIC ACTIVE AGENT PARTICLES BANK OF MONTREAL, AS COLLATERAL AGENT 2015-05-21 US disclosed
US-20140336571-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF HYDROPHOBIC ACTIVE AGENTS SURMODICS, INC. (US) 2014-11-13 US disclosed
US-20130190689-A1 DELIVERY OF COATED HYDROPHOBIC ACTIVE AGENT PARTICLES SURMODICS, INC. (US) 2013-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336571-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF HYDROPHOBIC ACTIVE AGENTS PAICS, HNRNPA1, INCENP GPR84 245/4885PLA2G1B 1940/4885PLA2G2A 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.