Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554458 | 0.80 | HPGD (0.52) | KMT2AHPGDSMN1; SMN2HTR6L3MBTL3 | |
| SCHEMBL63548 | 0.76 | — | — | |
| SCHEMBL894571 | 0.76 | — | — | |
| SCHEMBL12190269 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1950482 | 0.73 | HPGD (0.59) | KMT2AHPGDSMN1; SMN2HTR6L3MBTL3 | |
| Ammonia Solution, Strong SCHEMBL19410292 | 0.73 | HPGD (0.53) | KMT2AHPGDSMN1; SMN2HTR6L3MBTL3 | |
| Hydrochloric Acid SCHEMBL64625 | 0.73 | HPGD (0.59) | KMT2AHPGDSMN1; SMN2HTR6L3MBTL3 | |
| SCHEMBL1557587 | 0.71 | — | — | |
| SCHEMBL22804831 | 0.71 | MEN1 (0.32) | KMT2AMEN1 | |
| SCHEMBL13801432 | 0.70 | HTR6 (0.59) | KMT2AHPGDSMN1; SMN2HTR6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013108754-A1 | PYRAZINE CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2013-07-25 | — | — | WO | disclosed |