⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31374953 | 0.97 | GABRA1 (0.33) | — | |
| SCHEMBL11196042 | 0.91 | SLC6A1 (0.30) | — | |
| SCHEMBL8795601 | 0.84 | — | — | |
| SCHEMBL5376291 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL251470 | 0.78 | — | — | |
| SCHEMBL11049355 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL264764 | 0.73 | — | — | |
| SCHEMBL264006 | 0.73 | — | — | |
| SCHEMBL15134688 | 0.71 | KMT2A (0.39) | — | |
| SCHEMBL1192805 | 0.71 | GSR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109161028-B | Preparation method of photodegradable two-dimensional polymer with cucurbituril as structural unit | 四川大学 | 2020-12-08 | — | — | CN | claimed |
| CN-109161028-A | It is a kind of using Cucurbituril as the preparation method of the degradable type two-dimension polymer of structural unit | 四川大学 | 2019-01-08 | — | — | CN | claimed |
| EP-2905272-B1 | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | COVESTRO DEUTSCHLAND AG (DE) | 2016-11-23 | — | — | EP | claimed |
| US-9278906-B2 | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | BAYER MATERIALSCIENCE AG (DE) | 2016-03-08 | — | — | US | claimed |
| EP-2905272-A1 | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | Bayer MaterialScience AG (DE) | 2015-08-12 | — | — | EP | claimed |
| US-20150218083-A1 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES TO CYCLOALIPHATIC DI- AND POLYAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2015-08-06 | — | — | US | claimed |
| CN-104817459-A | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | BAYER MATERIALSCIENCE AG | 2015-08-05 | — | — | CN | claimed |
| CN-102464605-B | Preparation method of 4-nitro-piperidine derivative | WUXI APPTEC CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-103130708-A | Preparing method of N-t-butyloxycarboryl-4-nitro piperidine | WUXI APPTEC CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-102464605-A | Process for the preparation of 4-nitro-piperidine derivatives | WUXI APPTEC CO LTD | 2012-05-23 | — | — | CN | claimed |
| CN-119243183-A | Synthesis method of nitrosamine organic compound | 中国科学技术大学 | 2025-01-03 | — | — | CN | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| CN-109161028-B | Preparation method of photodegradable two-dimensional polymer with cucurbituril as structural unit | 四川大学 | 2020-12-08 | — | — | CN | disclosed |
| CN-104817459-B | The method for generating cyclic aliphatic two-and polyamines for Hydrogenated aromatic two-and polyamines | 科思创德国股份有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-109161028-A | It is a kind of using Cucurbituril as the preparation method of the degradable type two-dimension polymer of structural unit | 四川大学 | 2019-01-08 | — | — | CN | disclosed |
| US-6956042-B2 | N-aryl diazaspiracyclic compounds and methods of preparation and use thereof | TARGACEPT, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| CN-1665818-A | N-aryl diazaspiracyclic compounds and methods of preparation and use thereof | TARGACEPT INC (US) | 2005-09-07 | — | — | CN | disclosed |
| EP-1519939-A2 | N-ARYL DIAZASPIRACYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | Targacept, Inc. (US) | 2005-04-06 | — | — | EP | disclosed |
| US-20040067930-A1 | N-aryl diazaspiracyclic compounds and methods of preparation and use thereof | TARGACEPT, INC. | 2004-04-08 | — | — | US | disclosed |
| WO-2004005293-A2 | N-ARYL DIAZASPIRACYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | TARGACEPT, INC. (US) | 2004-01-15 | — | — | WO | disclosed |